-Description-
Bendamustine HCL CAS 3543-75-7, also known as Bendamustine hydrochloride, is a bifunctional alkylating agent. Its pharmacological action is to cross-link DNA single and double strands through alkylation, interfering with DNA function and DNA synthesis, thereby exerting anti-tumor effects. As a new generation of anticancer products, bendamustine hydrochloride has obvious therapeutic effects on a variety of cancers. Bendamustine hydrochloride can be used to treat various malignant tumors such as Hodgkin's disease, non-Hodgkin's lymphoma (NHL), multiple myeloma, chronic lymphocytic leukemia (CLL), and breast cancer.
-Certificate of Analysis-
Mellon is one of the leading bendamustine HCL powder manufacturers in China, we can provide high-quality bendamustine HCL at a competitive price. Here is the main specification for bendamustine hydrochloride powder as follows:
Test items |
Specifications |
Results |
Appearance |
White or off-white crystalline powder |
Conforms |
Identification | ||
HPLC High-performance liquid chromatograph |
The retention time of test sample major peak complies to reference standard |
Conforms |
Inspection | ||
Loss on drying |
No more than 1.0% |
0.40% |
Related impurity |
Total impurities no more than 1.5% |
0.50% |
Single impurity no more than 0.5% |
Conforms |
|
Heavy metals |
No more than 20ppm |
<10ppm |
Purity |
No less than 98.50% |
99.50% |
Conclusion: Conforms to the In-house standard |
-Usage-
Bendamustine hydrochloride has a good antitumor effect. As a single or in combination with chemotherapy, the response rates of this product for Hodgkin's lymphoma and non-Hodgkin's lymphoma were 61% to 97% and 41% to 48%, respectively.
Indications
1. Chronic lymphocytic leukemia (CLL);
2. Indolent B-cell non-Hodgkin's lymphoma (NHL) with disease progression after six months of Rituximab-containing therapy;
3. elderly multiple myeloma.
-Where to buy Bendamustine hydrochloride-
Mellon is a professional manufacturer and supplier of APIs and intermediates, we have rich stock of Bendamustine HCL CAS 3543-75-7 for sale, welcome to buy and wholesale cheap Bendamustine hydrochloride from us. If you are interested in our products or have any questions, please feel free to contact us!
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